1.what is purpura nephritis?

1.what is purpura nephritis?

Purpura Nephritis is also known as Henoch-Schonlein Purpura (HSP). It is a whole-body disease which is caused by necrotizing vasculitis, and it can not only affect kidneys but also affect the whole organs. The clinical symptoms include skin purpura, joint gall, abdominal pain and hematochezia. In the skin, the disease causes palpable purpura (small hemorrhages); often with joint and abdominal pain. With kidney involvement, there may be a loss of small amounts of blood and protein in the urine, but this usually goes unnoticed; in a small proportion of cases, the kidney involvement proceeds to chronic kidney disease. Purpura nephritis is often preceded by an infection, such as a throat infection.

However, the most obvious symptoms are hematuria and proteinuria which usually occurs after one month of the skin purpura presence. Purpura Nephritis develops to kidney failure easily, so once purpura nephritis patients found they have any symptom of kidney damage, they need to go to effective treatment as early as possible so as to prevent bad consequence.

2.What causes purpura nephritis?

This disease is an allergic reaction which may be caused by bacteria, germs, parasite and other infections. Or it can be caused due to patients being allergic to some medications and foods and also can be related to plant pollen, bugbite and the stimulation of cold. It is usually accompanied by the following factors, including:

1. Infections

One third patients have the history of upper respiratory tract infection. The common pathogenes include virus which refers to Coxsackievirus, EB Virus, adenovirus, varicella-zoster virus and hepatitis B virus etc, as well as bacteria like salmonella, legionella, hemolytic and streptococcus. In addition, myoplasma, amoeba and worm can also cause infection leading to Purpura Nephritis.

2. Some medications and foods

Some medications may result in allergy and cause Purpura Nephritis. The medications are like antibiotics, sulfonamides, isoniazide and captopril. Some people may be allergic to some foods such as fish, crabs and shrimps. A long -term of allergy may lead to the allergic reaction of Purpura Nephritis.

3. Stimulation is related to purpura nephritis

Some people can not bear some stimulation, including cold, plant pollen, animal feathers, mosquitoes and vaccination. These stimulation can cause the presence of purpura nephritis.